Cogent Food & Agriculture, 2016.

Collected literature on isoflavones and chronic diseases

Katie A. Miller, Farrell Frankel, Hitomi Takahashr, et al

Simmons College, S-334, Boston, MA 02115, USA

Isoflavones are organic compounds, which have been linked to the health benefits and prevention of many diseases. Common isoflavones are genistein, daidzein, and glycitein. Genistein has been researched in regard to its effect on the reduction of menopausal symptoms and reduction of cardiovascular risk factors in osteopenic, post-menopausal women. Research on daidzein focuses on bone mineral density implications in post-menopausal women, therapeutic effects early in prostate cancer, and protection against DMBA-induced mammary carcinogenesis. The most recent research on daidzein has implications for its effect on cardiovascular risk reduction. Research on glycitein focuses on it bioavailability, as well as its role in angiogenesis and invasion of malignant glioma cells. The health benefits of these specific isoflavones are instrumental in the prevention and treatment of many diseases. This review of literature focuses on the effects of genistein, daidzein, and glycitein on health outcomes, such as breast cancer, cardiovascular disease, and prostate cancer.

《权威杂志食品与农业》

关于异黄酮和慢性疾病的文献收集

西蒙斯学院 S-334，美国马萨诸塞州波士顿 02115，

异黄酮是有机化合物，其与许多疾病的健康益处和预防相关。常见的异黄酮是染料木黄酮，黄豆苷原和黄豆黄素。已经研究了染料木黄酮对减少绝经期症状和降低骨质减少，绝经后妇女的心血管危险因素相关。大豆黄酮的研究集中于绝经后妇女的骨矿物质密度的影响，早期在前列腺癌中的治疗作用和对DMBA诱导的乳腺癌发生的保护方面。最近的研究是黄豆苷原对其对心血管风险降低有影响。对黄豆黄素的研究集中在其生物利用度，以及其在血管发生和恶性神经胶质瘤细胞入侵中的作用。这些特定异黄酮的益处有助于许多疾病的预防和治疗。这篇文献综述集中在染料木素，黄豆苷原和黄豆黄素对健康结果的影响，如乳腺癌，心血管疾病和前列腺癌。